Integrin αvβ1 Modulation Affects Subtype B Avian Metapneumovirus Fusion Protein-mediated Cell-Cell Fusion and Virus Infection
نویسندگان
چکیده
منابع مشابه
Localization of a region in the fusion protein of avian metapneumovirus that modulates cell-cell fusion.
The genus Metapneumovirus within the subfamily Pneumovirinae of the family Paramyxoviridae includes two members, human metapneumovirus (hMPV) and avian metapneumovirus (aMPV), causing respiratory tract infections in humans and birds, respectively. Paramyxoviruses enter host cells by fusing the viral envelope with a host cell membrane. Membrane fusion of hMPV appears to be unique, in that fusion...
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Avian metapneumovirus (aMPV) represents one of the most prevalent diseases of poultry mainly in combination with other pathogens, and it is increasing among chickens. In the present study, the detection and characterization of an aMPV subtype B strain circulating in broiler flocks based on fusion (F) gene. In phylogenetic analysis, the isolates are located in B subtype cl...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2016
ISSN: 0021-9258
DOI: 10.1074/jbc.m115.711382